Vladimir B. Kobychev

Doctor of Sciences in Chemistry, Full Professor

Education and career

1977 - Graduated from the Chemical Faculty of Irkutsk State University

1977 - Software Engineer of ISU Computer Center

1980 - 1988 - Junior Researcher of the Laboratory of Quantum Chemistry

1988 - Defense of a thesis for the degree of Candidate of Sciences (Ph.D.) in Chemistry. Dissertation topic: in Russian "Неэмпирическое квантовохимическое изучение координации ацетилена и винилидена металлами первого переходного периода", in English "Non-empirical quantum-chemical study of the acetylene and vinylidene coordination  by the metals of the first transition period".

1989 - Senior Researcher of the Laboratory of Quantum Chemistry

1993 - present - Leading Researcher of the Laboratory of Quantum Chemistry

1998 г. - Academic title of Docent (Assistant Professor) in the department of physical chemistry

2004 - Defense of a thesis for the degree of Doctor of Sciences in Chemistry. Dissertation topic: in Russian "Квантовохимическое исследование изомерных превращений ненасыщенных гетероорганических соединений с участием анионов", in English "Quantum-chemical study of isomeric transformations of unsaturated heteroorganic compounds with the participation of anions"

2005 - 2014 - Professor of the Department of Physical Methods of Analysis, Chemical Faculty, ISU

2014 - 2015 - Professor of the Department of Theoretical and Applied Organic Chemistry and Polymerization Processes, Chemical Faculty, ISU

2015 - present - Professor of the Department of Physical and Colloid Chemistry, Chemical Faculty, ISU

Research Interests – quantum chemistry, reaction mechanisms of organic compounds, in particular, carried out in superbasic media.

Main scientific achievements

Within the framework of a unified approach, the processes of [1,3] -protropic rearrangement in alkenes, alkynes, azines, oximes, oxime ethers, amidoximes and O-vinyl amidoximes were studied.

Non-traditional mechanisms of prototropic isomerization of alkenes and alkynes in the presence of bases with the participation of hydroxide and alkoxide ions are considered, which allow, in particular, to explain the patterns observed during reactions using deuterated media, bases and / or substrates. Regularities are formulated that determine the direction of these transformations depending on the nature of the heteroatom center.

Bibliography – more than 100 scientific and educational publications.

Author Profiles:

Recent Publications

2018

• V.B. Orel, N.M. Vitkovskaya, V.B. Kobychev, and B.A. Trofimov / Transition-Metal-Free C-Vinylation of Ketones with Acetylenes: A Quantum-Chemical Rationalization of Similarities and Differences in Catalysis by Superbases MOH/DMSO and tBuOM/DMSO (M = Na, K) // J. Org. Chem. – 2018 – V.83, N.7 – P.3719-3726
• N.M. Vitkovskaya, V.B. Orel, V.B. Kobychev, E.Yu. Schmidt, and B.A. Trofimov / Two classes of heterocycles – 6,8-dioxabicyclo[3.2.1]octanes and cyclopentenols from the same reagents: a quantum-chemical comparison of mechanism // Int. J. Quantum Chem. – 2018 – e25689 (1-10).

2017

• N.M. Vitkovskaya, V.B. Kobychev, A.S. Bobkov, V.B. Orel, E.Y. Schmidt, B.A. Trofimov / Nucleophilic Addition of Ketones To Acetylenes and Allenes: A Quantum-Chemical Insight // J. Org. Chem. — 2017. — V. 82, N. 23. — P. 12467–12476.
• В.Б. Кобычев, В.Б. Орел, Д.В. Занков, Н.М. Витковская, Б.А. Трофимов / Квантово-химическое моделирование катализируемых супероснованием реакций ацетофенона и метилмезитилкетона с ацетиленом // Изв. АН, Сер. хим. — 2017. — N. 12. — P. 2227–2233.
• N. M. Vitkovskaya, V. B. Kobychev, A. D. Skitnevskaya, V. B. Orel, A. S. Bobkov, A. A. Zubarev, and B. A. Trofimov / Synthesis of divinyl sulphide via addition of hydrogen sulfide anion to acetylene in alkaline metal hydroxide/DMSO superbasic system: A quantum-chemical insight // Tetrahedron Lett. – 2017. – Vol. 58, No 1 – P. 92–96.
• N. M. Vitkovskaya, V. B. Orel, V. B. Kobychev, A. S. Bobkov, E. Yu. Larionova, and B. A. Trofimov / Exploring acetylene chemistry in superbasic media: a theoretical study of water impact on vinylation and ethynylation reactions with acetylene in KOH/DMSO and NaOH/DMSO systems // J. Phys. Org. Chem. – 2017. –No 30. – P. 3669 (1-11) doi: 10.1002/poc.3669.

2016

• B. A. Trofimov, L. V. Andriyankova, L. P. Nikitina, K. V. Belyaeva, A. G. Mal'kina, A. V. Afonin, I. A. Ushakov, V. B. Kobychev, V. M. Muzalevskiy, V. G. Nenajdenko / Reaction of imidazole derivatives with trifluoromethylated arylacetylenes // J. Fluor. Chem.– 2016.–Vol. 188.– P. 157–163.
• N.M. Vitkovskaya, E.Yu. Larionova, V.B. Kobychev, E.Yu. Shmidt, and B.A. Trofimov / Formation mechanism and conformation structure of 2,3,4-trimethyl-1,5-di(thiophen-2-yl)pentane-1,5-dione: quantum chemical study // Russ. Chem. Bull. – 2016. – Vol. 65, No 2 – P. 394–400.

2015

• В.Б. Кобычев, В.Б. Орел, Н.М. Витковская, Е.Ю. Шмидт, Б.А. Трофимов / Квантовохимическое исследование стереоселективности нуклеофильного присоединения 2-метилциклогексанона к фенилацетилену // Докл. АН. – 2015 – Т. 461, № 6. – С. 669–672.
• В.Б. Кобычев, Н.М. Витковская, В.Б. Орел, Е.Ю. Шмидт, Б.А. Трофимов / Квантово-химическое реакций алкил- и арилкетонов с фенилацетиленом под действием супероснования KOH—DMSO // Изв. АН. Сер. хим. – 2015. – № 3 – С. 518–524.
• D. A. Shabalin, M.Yu. Dvorko, E.Yu. Schmidt, I. A. Ushakov, N.I. Protsuk, V. B. Kobychev, D.Yu. Soshnikov, A.B. Trofimov, N. M. Vitkovskaya, A. I. Mikhaleva, B. A. Trofimov / 3H-Pyrroles from ketoximes and acetylene: synthesis, stability and quantum-chemical insight// Tetrahedron. ­– 2015. – Vol. 71. – P. 3273–3281

2014

• В.Б. Кобычев, Н.М. Витковская. Основы теории групп и ее химические приложения – ООО «Издательство «Аспринт», 2014. – 108 с.
• Н.М. Витковская, Е.Ю. Ларионова, В.Б. Кобычев, А.Д. Скитневская, Б.А. Трофимов / Квантовохимическое исследование селективности реакций нуклеофильного присоединения метантиола к замещенным ацетиленам в суперосновной среде KOH/DMSO // Докл. АН. – 2014. – Т.456, №5. – С. 549–551.
• В. Б. Кобычев, В. Б. Орел, Н. М. Витковская, Б.А. Трофимов / Теоретическое исследование реакций ацетона с ацетиленом и фениацетиленом в суперосновной системе KOH/DMSO // Докл. АН. – 2014. – Т.457, №2. – С. 179–181.
• B.A. Trofimov, L.A. Oparina, O.A. Tarasova, A.V. Artem'ev, V.B. Kobychev,Yu.V. Gatilov, A.I. Albanov, N.K. Gusarova / Tuneable superbase-catalyzed vinylation of α-hydroxyalkylferrocenes with alkynes // Tetrahedron.– 2014.– Vol. 70, Iss. 52 – P. 5954-5960.