Isu - News - Medicinal substances detected in Baikal amphipods by ISU biologists Medicinal substances detected in Baikal amphipods by ISU biologists
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IRKUTSK STATE UNIVERSITY
Medicinal substances detected in Baikal amphipods by ISU biologists
8 May 2026

Scientists of the Research and Education Centre (REC) “Bioorganics” at Irkutsk State University have analysed endemic Baikal amphipods from different areas of the lake and confirmed that pharmaceuticals enter living organisms even in the deepest and cleanest water in the world.

Tamara Telnova, researcher at the REC “Bioorganics”:

The presence of ibuprofen and its metabolites has been detected not only in the coastal zone but also in deep-water organisms that live at considerable depth.

In addition, scientists noted that they need to hold laboratory toxicological experiments on endemic amphipods, assessing the impact on mortality, reproduction and antioxidant systems, as well as clarify the role of symbionts in the metabolism of ibuprofen.

The scientists performed a quantitative analysis of ibuprofen in 218 specimens of Baikal amphipods using chromatography-mass spectrometry methods. They found that concentrations vary from 4.19 to 1 151 ng/g raw weight; in spring, levels are significantly higher than in autumn (p=0.001); in the genus Brandtia, ibuprofen levels are four times higher than in Eulimnogammarus; the metabolite 3-carboxyibuprofen was detected. This indicates that amphipods or their symbionts may be metabolizing ibuprofen.

The scientific article by Irkutsk biologists is published in the scientific journal “PeerJ”.

*PeerJ is a peer-reviewed open access scientific journal. The journal considers articles in biology and life sciences, medicine and healthcare, ecology, chemistry and materials science, engineering and technology. Articles are published continuously, with new articles appearing Monday through Friday.

Background: Amphipods are a trophic link for omul and nerpa. According to global scientific data, ibuprofen disrupts reproduction (reduces testosterone, suppresses ovarian maturation), causes oxidative stress and embryo malformations in crustaceans. The presence of a metabolite suggests possible additional toxicity. Direct studies on Baikal species are not yet available.

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